Spirespy.com has officially launched with Slay the Spire 2! Go to site →
Relic images have been fixed, if you are not seeing the images try [Shift] + [F5] or [Cmd] + [Shift] + [R].
relic
any
uncommon

Blue Candle
uncommon
Curse cards can now be played. Playing a Curse will make you lose 1 HP and Exhausts the card.
C-
D+
D+
D+
No any, colorless or curse cards supersynergies.

Blood Vial
common
At the start of each combat, heal 2 HP.
C-
B-
C+
B-

Juzu Bracelet
common
Regular enemy combats are no longer encountered in ? rooms.
B
B
B
B

Regal Pillow
common
Heal an additional 15 HP when you Rest.
A-
A
A
A

Singing Bowl
common
When adding cards to your deck, you may gain +2 Max HP instead.
S
S
S
S

Strawberry
common
Raise your Max HP by 7.
C
C+
C+
C+

Centennial Puzzle
uncommon
The first time you lose HP each combat, draw 3 cards.
B
B-
B-
B-

Darkstone Periapt
uncommon
Whenever you obtain a Curse, increase your Max HP by 6.
D+
D+
D+
D+

Meat on the Bone
uncommon
If your HP is at or below 50% at the end of combat, heal 12 HP.
A-
A
A-
A

Pantograph
uncommon
At the start of boss combats, heal 25 HP.
B-
B+
B+
B+

Pear
uncommon
Raise your Max HP by 10.
B
B+
B+
B+

Bird-Faced Urn
rare
Whenever you play a Power, heal 2 HP.
B-
B+
A-
B+

Dead Branch
rare
Whenever you Exhaust a card, add a random card to your hand.
S+
S
B-
S

Du-Vu Doll
rare
For each Curse in your deck, start each combat with 1 additional Strength.
B-
C+
C
B

Mango
rare
Raise your Max HP by 14.
B-
B
B
B

Calling Bell
boss
Upon pickup, obtain an unremoveable Curse and 3 relics.
C+
C
C
C

Cursed Key
boss
Gain 1 Energy at the start of each turn. Whenever you open a non-boss chest, obtain a Curse.
A
A
A
A

Eternal Feather
uncommon
For every 5 cards in your deck, heal 3 HP whenever you enter a Rest Site.
B
B+
B+
B+

Lizard Tail
rare
When you would die, heal to 50% of your Max HP instead (works once).
B
B
B
B

Tiny House
boss
Obtain 1 potion. Gain 30 Gold. Raise your Max HP by 5. Obtain 1 card. Upgrade 1 Random card.
C-
C-
C-
C-

Bloody Idol
event
Whenever you gain Gold, heal 5 HP.
B-
B+
B+
B+

Lee's Waffle
shop
Raise your Max HP by 7 and heal all of your HP.
D+
D+
D+
D+

Toy Ornithopter
shop
Whenever you use a potion, heal 5 HP.
C-
C
C
C

Face of Cleric
event
Raise your Max HP by 1 after each combat.
B
B+
B
B+

Meal Ticket
shop
Whenever you enter a shop room, heal 15 hp.
C
C+
C+
C+

Tungsten Rod
rare
Whenever you would lose HP, lose 1 less.
S
S-
S-
S-

Blood Vial
common
At the start of each combat, heal 2 HP.
C-
B-
C+
B-

Juzu Bracelet
common
Regular enemy combats are no longer encountered in ? rooms.
B
B
B
B

Regal Pillow
common
Heal an additional 15 HP when you Rest.
A-
A
A
A

Singing Bowl
common
When adding cards to your deck, you may gain +2 Max HP instead.
S
S
S
S

Strawberry
common
Raise your Max HP by 7.
C
C+
C+
C+

Centennial Puzzle
uncommon
The first time you lose HP each combat, draw 3 cards.
B
B-
B-
B-

Darkstone Periapt
uncommon
Whenever you obtain a Curse, increase your Max HP by 6.
D+
D+
D+
D+

Meat on the Bone
uncommon
If your HP is at or below 50% at the end of combat, heal 12 HP.
A-
A
A-
A

Pantograph
uncommon
At the start of boss combats, heal 25 HP.
B-
B+
B+
B+

Pear
uncommon
Raise your Max HP by 10.
B
B+
B+
B+

Bird-Faced Urn
rare
Whenever you play a Power, heal 2 HP.
B-
B+
A-
B+

Dead Branch
rare
Whenever you Exhaust a card, add a random card to your hand.
S+
S
B-
S

Du-Vu Doll
rare
For each Curse in your deck, start each combat with 1 additional Strength.
B-
C+
C
B

Mango
rare
Raise your Max HP by 14.
B-
B
B
B

Calling Bell
boss
Upon pickup, obtain an unremoveable Curse and 3 relics.
C+
C
C
C

Cursed Key
boss
Gain 1 Energy at the start of each turn. Whenever you open a non-boss chest, obtain a Curse.
A
A
A
A

Eternal Feather
uncommon
For every 5 cards in your deck, heal 3 HP whenever you enter a Rest Site.
B
B+
B+
B+

Lizard Tail
rare
When you would die, heal to 50% of your Max HP instead (works once).
B
B
B
B

Tiny House
boss
Obtain 1 potion. Gain 30 Gold. Raise your Max HP by 5. Obtain 1 card. Upgrade 1 Random card.
C-
C-
C-
C-

Bloody Idol
event
Whenever you gain Gold, heal 5 HP.
B-
B+
B+
B+

Lee's Waffle
shop
Raise your Max HP by 7 and heal all of your HP.
D+
D+
D+
D+

Toy Ornithopter
shop
Whenever you use a potion, heal 5 HP.
C-
C
C
C

Face of Cleric
event
Raise your Max HP by 1 after each combat.
B
B+
B
B+

Meal Ticket
shop
Whenever you enter a shop room, heal 15 hp.
C
C+
C+
C+

Tungsten Rod
rare
Whenever you would lose HP, lose 1 less.
S
S-
S-
S-

Burning Blood
starter
At the end of combat, heal 6 HP.

Runic Cube
uncommon
Whenever you lose HP, draw 1 card.

Self-Forming Clay
uncommon
Whenever you lose HP in combat, gain 3 Block next turn.

Charon's Ashes
rare
Whenever you Exhaust a card, deal 3 damage to ALL enemies.

Black Blood
boss
Replaces Burning Blood. At the end of combat, heal 12 HP.